Steve Carell
Gru (voice)
Kristen Wiig
Lucy (voice)
Benjamin Bratt
Eduardo/El Macho (voice)
Miranda Cosgrove
Margo (voice)
Dana Gaier
Edith (voice)
Elsie Fisher
Agnes (voice)
Russell Brand
Dr. Nefario (voice)
Ken Jeong
Floyd (voice)
Steve Coogan
Silas (voice)
Moises Arias
Antonio (voice)
Nasim Pedrad
Jillian (voice)
Kristen Schaal
Shannon (voice)
Pierre Coffin
Kevin / Bob / Stuart / Additional Minions / Evil Minions (voice)
Chris Renaud
Additional Minions / Evil Minions / Italian Waiter (voice)
Nickolai Stoilov
Arctic Lab Guards (voice)
Vanessa Bayer
Flight Attendant (voice)
Ava Acres
Additional Voices (voice)
Lori Alan
Additional Voices (voice)
Jack Angel
Additional Voices (voice)
Eva Bella
Additional Voices (voice)
Georgia Cook
Additional Voices (voice)
John Cygan
Additional Voices (voice)
Debi Derryberry
Additional Voices (voice)
Jess Harnell
Additional Voices (voice)
Danny Mann
Additional Voices (voice)